28,541 XNAS Volume
XNAS 21 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Matthew K. Szot | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Aug 2024 | 12,090 | 12,090 | - | - | Stock Option (right to buy) | |
| Thomas C. Chesterman | CFO & Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Aug 2024 | 24,170 | 24,170 | - | - | Stock Option (right to buy) | |
| Jake Leach | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Aug 2024 | 23,894 | 23,894 | - | - | Stock Option (right to buy) | |
| Jamie Bechtel Morrison | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Aug 2024 | 12,090 | 12,090 | - | - | Stock Option (right to buy) | |
| Phillip Nicholas Grandinetti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Aug 2024 | 14,672 | 14,672 | - | - | Stock Option (right to buy) | |
| Joel Fruendt | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Aug 2024 | 56,396 | 56,396 | - | - | Stock Option (right to buy) | |
| Jake Leach | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Apr 2024 | 4,469 | 4,469 | - | - | Stock Option (right to buy) | |
| Phillip Nicholas Grandinetti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Apr 2024 | 4,469 | 4,469 | - | - | Stock Option (right to buy) | |
| Matthew K. Szot | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Jun 2023 | 39,402 | 39,402 | - | - | Stock Option (right to buy) | |
| Jake Leach | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Jun 2023 | 41,010 | 41,010 | - | - | Stock Option (right to buy) | |
| Jamie Bechtel Morrison | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Jun 2023 | 44,226 | 44,226 | - | - | Stock Option (right to buy) | |
| Delphine Francois Chiavarini | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Jun 2023 | 26,536 | 26,536 | - | - | Stock Option (right to buy) | |
| Phillip Nicholas Grandinetti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Jun 2023 | 48,247 | 48,247 | - | - | Stock Option (right to buy) | |
| Thomas C. Chesterman | CFO & Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Dec 2022 | 34,750 | 34,750 | - | - | Stock Option (right to buy) | |
| Nicole C Williams | Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Dec 2022 | 26,500 | 26,500 | - | - | Stock Option (right to buy) | |
| Joel Fruendt | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Dec 2022 | 18,799 | 18,800 (0%) | 0% | 0 | Common Stock | |
| Marc Dumont | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 96,218 | 96,218 | - | - | Stock Option (right to buy) | |
| Matthew K. Szot | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 209,025 | 209,025 | - | - | Stock Option (right to buy) | |
| Jake Leach | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 199,071 | 199,071 | - | - | Stock Option (right to buy) | |
| Jamie Bechtel Morrison | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 215,660 | 215,660 | - | - | Stock Option (right to buy) | |
| Delphine Francois Chiavarini | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 129,396 | 129,396 | - | - | Stock Option (right to buy) | |
| Phillip Nicholas Grandinetti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 252,157 | 252,157 | - | - | Stock Option (right to buy) | |
| Kathleen Claire Kavanagh | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 142,668 | 142,668 | - | - | Stock Option (right to buy) | |
| Kenneth S. Siegel | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2022 | 150,000 | 150,000 | - | - | Stock Option (right to buy) | |
| Thomas C. Chesterman | CFO & Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2022 | 60,000 | 60,000 | - | - | Stock Option (right to buy) | |
| Kim Patrice Wolin | EVP and Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2022 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Nicole C Williams | Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2022 | 60,000 | 60,000 | - | - | Stock Option (right to buy) | |
| Jake Leach | Director | Purchase of securities on an exchange or from another person at price $ 1.54 per share. | 16 Aug 2021 | 50,000 | 50,000 (0%) | 0% | 1.5 | 76,885 | Common Stock |
| Jake Leach | Director | Purchase of securities on an exchange or from another person at price $ 1.54 per share. | 16 Aug 2021 | 50,000 | 150,000 (0%) | 0% | 1.5 | 77,095 | Common Stock |
| Jake Leach | Director | Purchase of securities on an exchange or from another person at price $ 1.50 per share. | 16 Aug 2021 | 50,000 | 100,000 (0%) | 0% | 1.5 | 74,785 | Common Stock |
| Marc Dumont | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2021 | 34,817 | 34,817 | - | - | Stock Option (right to buy) | |
| Matthew K. Szot | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2021 | 66,470 | 66,470 | - | - | Stock Option (right to buy) | |
| Jake Leach | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2021 | 33,762 | 72,800 | - | - | Stock Option (right to buy) | |
| Jake Leach | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2021 | 39,038 | 39,038 | - | - | Stock Option (right to buy) | |
| Jamie Bechtel Morrison | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2021 | 72,800 | 72,800 | - | - | Stock Option (right to buy) | |
| Delphine Francois Chiavarini | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2021 | 45,368 | 45,368 | - | - | Stock Option (right to buy) | |
| Phillip Nicholas Grandinetti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2021 | 41,148 | 41,148 | - | - | Stock Option (right to buy) | |
| Phillip Nicholas Grandinetti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2021 | 39,038 | 80,186 | - | - | Stock Option (right to buy) | |
| Kathleen Claire Kavanagh | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2021 | 45,368 | 45,368 | - | - | Stock Option (right to buy) | |
| Nicole C Williams | Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jun 2021 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Kenneth S. Siegel | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2021 | 120,000 | 120,000 | - | - | Stock Option (right to buy) | |
| Kim Patrice Wolin | EVP & Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Apr 2021 | 30,738 | 0 | - | - | Restricted Stock Units | |
| Kim Patrice Wolin | EVP & Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.66 per share. | 29 Apr 2021 | 10,454 | 26,147 (0%) | 0% | 1.7 | 17,354 | Common Stock |
| Kim Patrice Wolin | EVP & Secretary | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Apr 2021 | 30,738 | 36,601 (0%) | 0% | 0 | Common Stock | |
| Phillip Nicholas Grandinetti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2021 | 6,686 | 6,686 | - | - | Stock Option (right to buy) | |
| Kathleen Claire Kavanagh | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2021 | 1,070 | 1,070 | - | - | Stock Option (right to buy) | |
| Jake Leach | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Nov 2020 | 27,046 | 27,046 | - | - | Stock Option (right to buy) | |
| Phillip Nicholas Grandinetti | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Nov 2020 | 27,046 | 27,046 | - | - | Stock Option (right to buy) | |
| Kathleen Claire Kavanagh | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Nov 2020 | 16,099 | 16,099 | - | - | Stock Option (right to buy) | |
| Kenneth S. Siegel | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Jul 2020 | 101,965 | 101,965 | - | - | Stock Option (right to buy) | |
| Thomas C. Chesterman | CFO & Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Jul 2020 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Kim Patrice Wolin | EVP & Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2020 | 30,738 | 30,738 | - | - | Restricted Stock Units | |
| Jamie Bechtel Morrison | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jul 2020 | 2,921 | 2,921 | - | - | Stock Option (right to buy) | |
| Marc Dumont | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jul 2020 | 24,098 | 24,098 | - | - | Stock Option (right to buy) | |
| Matthew K. Szot | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jul 2020 | 31,401 | 31,401 | - | - | Stock Option (right to buy) | |
| Julia Williams | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jul 2020 | 21,177 | 21,177 | - | - | Stock Option (right to buy) | |
| Jamie Bechtel Morrison | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jul 2020 | 40,164 | 40,164 | - | - | Stock Option (right to buy) | |
| Delphine Francois Chiavarini | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jul 2020 | 28,480 | 28,480 | - | - | Stock Option (right to buy) | |
| Marc Dumont | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2020 | 564 | 0 | - | - | Restricted Stock Units | |
| Marc Dumont | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2020 | 564 | 1,337 (0%) | 0% | 0 | Common Stock | |
| Matthew K. Szot | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2020 | 846 | 4,658 (0%) | 0% | 0 | Common Stock | |
| Matthew K. Szot | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2020 | 846 | 0 | - | - | Restricted Stock Units | |
| Julia Williams | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2020 | 423 | 8,161 (0%) | 0% | 0 | Common Stock | |
| Julia Williams | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2020 | 423 | 0 | - | - | Restricted Stock Units | |
| Jamie Bechtel Morrison | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2020 | 1,198 | 2,812 (0%) | 0% | 0 | Common Stock | |
| Jamie Bechtel Morrison | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2020 | 1,198 | 0 | - | - | Restricted Stock Units | |
| Delphine Francois Chiavarini | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2020 | 846 | 1,314 (0%) | 0% | 0 | Common Stock | |
| Delphine Francois Chiavarini | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2020 | 846 | 0 | - | - | Restricted Stock Units | |
| Steven C. Krause | EVP, Sales and Marketing | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Apr 2020 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Loretta P. Mayer | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.83 per share. | 21 Oct 2019 | 6,000 | 335,165 (1%) | 0% | 0.8 | 4,980 | Common Stock |
| Loretta P. Mayer | Director, Chief Scientific Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 21 Oct 2019 | 30,000 | 341,165 (1%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Pres. & Chief Research Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 02 Oct 2019 | 50,000 | 320,091 (1%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Pres. & Chief Research Officer | Sale of securities on an exchange or to another person at price $ 0.93 per share. | 02 Oct 2019 | 6,000 | 370,091 (1%) | 0% | 0.9 | 5,575 | Common Stock |
| Thomas C. Chesterman | CFO & Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Sep 2019 | 50,000 | 50,000 | - | - | Stock Option (right to buy) | |
| Kim Patrice Wolin | EVP & Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Sep 2019 | 40,000 | 40,000 | - | - | Stock Option (right to buy) | |
| Loretta P. Mayer | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 1.24 per share. | 14 Aug 2019 | 20,000 | 391,165 (1%) | 0% | 1.2 | 24,756 | Common Stock |
| Loretta P. Mayer | Director, Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 1.19 per share. | 14 Aug 2019 | 20,000 | 371,165 (1%) | 0% | 1.2 | 23,734 | Common Stock |
| Cheryl A. Dyer | Pres. & Chief Research Officer | Sale of securities on an exchange or to another person at price $ 1.18 per share. | 14 Aug 2019 | 20,000 | 396,091 (1%) | 0% | 1.2 | 23,622 | Common Stock |
| Cheryl A. Dyer | Pres. & Chief Research Officer | Sale of securities on an exchange or to another person at price $ 1.20 per share. | 14 Aug 2019 | 20,000 | 376,091 (1%) | 0% | 1.2 | 24,100 | Common Stock |
| Kenneth S. Siegel | Director, CEO | Purchase of securities on an exchange or from another person at price $ 1.35 per share. | 16 Jul 2019 | 696,296 | 702,558 (2%) | 2% | 1.4 | 940,000 | Common Stock |
| Loretta P. Mayer | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2019 | 18,336 | 419,708 (1%) | 0% | 0 | Common Stock | |
| Loretta P. Mayer | Director, Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2019 | 18,336 | 0 | - | - | Restricted Stock Units | |
| Loretta P. Mayer | Director, Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.80 per share. | 30 Jun 2019 | 8,543 | 411,165 (1%) | 0% | 1.8 | 15,377 | Common Stock |
| Cheryl A. Dyer | Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2019 | 18,336 | 424,962 (1%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2019 | 18,336 | 0 | - | - | Restricted Stock Units | |
| Cheryl A. Dyer | Pres. & Chief Research Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.80 per share. | 30 Jun 2019 | 8,871 | 416,091 (1%) | 0% | 1.8 | 15,968 | Common Stock |
| Kenneth S. Siegel | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2019 | 6,262 | 0 | - | - | Restricted Stock Units | |
| Kenneth S. Siegel | Director, CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2019 | 6,262 | 6,262 (0%) | 0% | 0 | Common Stock | |
| Marc Dumont | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2019 | 8,791 | 0 | - | - | Restricted Stock Units | |
| Marc Dumont | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2019 | 11,268 | 11,268 | - | - | Restricted Stock Units | |
| Marc Dumont | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2019 | 22,896 | 22,896 | - | - | Stock Option (right to buy) | |
| Marc Dumont | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2019 | 8,791 | 15,454 (0%) | 0% | 0 | Common Stock | |
| Matthew K. Szot | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2019 | 16,901 | 16,901 | - | - | Restricted Stock Units | |
| Matthew K. Szot | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2019 | 13,187 | 76,238 (0%) | 0% | 0 | Common Stock | |
| Matthew K. Szot | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2019 | 13,187 | 0 | - | - | Restricted Stock Units | |
| Matthew K. Szot | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2019 | 31,618 | 31,618 | - | - | Stock Option (right to buy) | |
| Julia Williams | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2019 | 7,692 | 154,779 (0%) | 0% | 0 | Common Stock | |
| Julia Williams | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2019 | 7,692 | 0 | - | - | Restricted Stock Units | |
| Julia Williams | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2019 | 8,451 | 8,451 | - | - | Restricted Stock Units | |
| Julia Williams | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2019 | 18,535 | 18,535 | - | - | Stock Option (right to buy) | |
| Jamie Bechtel Morrison | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2019 | 42,521 | 42,521 | - | - | Stock Option (right to buy) | |
| Jamie Bechtel Morrison | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2019 | 23,944 | 23,944 | - | - | Restricted Stock Units | |
| Jamie Bechtel Morrison | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2019 | 17,308 | 0 | - | - | Restricted Stock Units | |
| Jamie Bechtel Morrison | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2019 | 17,308 | 32,261 (0%) | 0% | 0 | Common Stock | |
| Delphine Francois Chiavarini | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2019 | 31,618 | 31,618 | - | - | Stock Option (right to buy) | |
| Delphine Francois Chiavarini | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2019 | 9,341 | 0 | - | - | Restricted Stock Units | |
| Delphine Francois Chiavarini | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Jun 2019 | 9,341 | 9,341 (0%) | 0% | 0 | Common Stock | |
| Delphine Francois Chiavarini | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2019 | 16,901 | 16,901 | - | - | Restricted Stock Units | |
| Kenneth S. Siegel | Director, CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2019 | 700,000 | 700,000 | - | - | Stock Option (right to buy) | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 30 Mar 2019 | 1,000 | 392,691 (1%) | 0% | 0 | Common Stock | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Mar 2019 | 18,333 | 18,336 | - | - | Restricted Stock Units | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.22 per share. | 30 Mar 2019 | 9,652 | 401,372 (1%) | 0% | 1.2 | 11,775 | Common Stock |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Mar 2019 | 18,333 | 411,024 (1%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Mar 2019 | 18,333 | 18,336 | - | - | Restricted Stock Units | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.22 per share. | 30 Mar 2019 | 9,972 | 406,626 (1%) | 0% | 1.2 | 12,166 | Common Stock |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Mar 2019 | 18,333 | 416,598 (1%) | 0% | 0 | Common Stock | |
| Kenneth S. Siegel | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2019 | 8,218 | 8,218 | - | - | Stock Option (right to buy) | |
| Kenneth S. Siegel | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2019 | 6,262 | 6,262 | - | - | Restricted Stock Units | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Dec 2018 | 18,333 | 402,207 (1%) | 0% | 0 | Common Stock | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.58 per share. | 31 Dec 2018 | 8,516 | 393,691 (1%) | 0% | 0.6 | 4,898 | Common Stock |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Dec 2018 | 18,333 | 36,669 | - | - | Restricted Stock Units | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2018 | 50,000 | 383,874 (1%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.58 per share. | 31 Dec 2018 | 8,846 | 398,265 (1%) | 0% | 0.6 | 5,087 | Common Stock |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Dec 2018 | 18,333 | 407,111 (1%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2018 | 50,000 | 388,778 (1%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Dec 2018 | 18,333 | 36,669 | - | - | Restricted Stock Units | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Sep 2018 | 18,333 | 55,002 | - | - | Restricted Stock Units | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.69 per share. | 30 Sep 2018 | 4,464 | 433,874 (1%) | 0% | 0.7 | 3,080 | Common Stock |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Sep 2018 | 18,333 | 438,338 (1%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Sep 2018 | 18,333 | 443,572 (1%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.69 per share. | 30 Sep 2018 | 4,794 | 438,778 (1%) | 0% | 0.7 | 3,308 | Common Stock |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Sep 2018 | 18,333 | 55,002 | - | - | Restricted Stock Units | |
| Julia Williams | None | Purchase of securities on an exchange or from another person at price $ 1.15 per share. | 13 Aug 2018 | 1,000 | 5,000 (0%) | 0% | 1.2 | 1,150 | Common Stock |
| Julia Williams | None | Purchase of securities on an exchange or from another person at price $ 1.15 per share. | 13 Aug 2018 | 6,000 | 147,087 (0%) | 0% | 1.2 | 6,900 | Common Stock |
| Julia Williams | None | Purchase of securities on an exchange or from another person at price $ 1.15 per share. | 13 Aug 2018 | 4,000 | 8,000 (0%) | 0% | 1.2 | 4,600 | Common Stock |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.63 per share. | 30 Jun 2018 | 4,299 | 420,005 (2%) | 0% | 1.6 | 7,007 | Common Stock |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2018 | 18,333 | 73,335 | - | - | Restricted Stock Units | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2018 | 18,333 | 424,304 (2%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2018 | 18,333 | 73,335 | - | - | Restricted Stock Units | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.63 per share. | 30 Jun 2018 | 4,629 | 425,239 (2%) | 0% | 1.6 | 7,545 | Common Stock |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2018 | 18,333 | 429,868 (2%) | 0% | 0 | Common Stock | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 2.13 per share. | 21 Jun 2018 | 6,000 | 405,971 (2%) | 0% | 2.1 | 12,780 | Common Stock |
| Grover Turnbow Wickersham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2018 | 15,683 | 15,683 | - | - | Stock Option (right to buy) | |
| Grover Turnbow Wickersham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2018 | 6,593 | 6,593 | - | - | Restricted Stock Units | |
| Marc Dumont | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2018 | 8,791 | 8,791 | - | - | Restricted Stock Units | |
| Marc Dumont | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2018 | 19,373 | 19,373 | - | - | Stock Option (right to buy) | |
| Matthew K. Szot | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2018 | 13,187 | 13,187 | - | - | Restricted Stock Units | |
| Matthew K. Szot | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2018 | 26,753 | 26,753 | - | - | Stock Option (right to buy) | |
| Julia Williams | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2018 | 17,528 | 17,528 | - | - | Stock Option (right to buy) | |
| Julia Williams | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2018 | 7,692 | 7,692 | - | - | Restricted Stock Units | |
| Jamie Bechtel Morrison | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2018 | 17,308 | 17,308 | - | - | Restricted Stock Units | |
| Jamie Bechtel Morrison | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2018 | 33,672 | 33,672 | - | - | Stock Option (right to buy) | |
| Delphine Francois Chiavarini | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2018 | 9,341 | 9,341 | - | - | Restricted Stock Units | |
| Delphine Francois Chiavarini | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2018 | 20,295 | 20,295 | - | - | Stock Option (right to buy) | |
| Jamie Bechtel Morrison | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Jun 2018 | 12,820 | 12,820 (0%) | 0% | 0 | Common Stock | |
| Jamie Bechtel Morrison | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Jun 2018 | 12,820 | 0 | - | - | Restricted Stock Units | |
| Grover Turnbow Wickersham | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 May 2018 | 3,577 | 290,263 (1%) | 0% | 0 | Common Stock | |
| Grover Turnbow Wickersham | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 May 2018 | 3,577 | 0 | - | - | Restricted Stock Units | |
| Marc Dumont | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 May 2018 | 3,577 | 0 | - | - | Restricted Stock Units | |
| Marc Dumont | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 May 2018 | 3,577 | 6,663 (0%) | 0% | 0 | Common Stock | |
| Matthew K. Szot | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 May 2018 | 3,577 | 63,051 (0%) | 0% | 0 | Common Stock | |
| Matthew K. Szot | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 May 2018 | 3,577 | 0 | - | - | Restricted Stock Units | |
| Julia Williams | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 May 2018 | 3,577 | 141,087 (0%) | 0% | 0 | Common Stock | |
| Julia Williams | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 May 2018 | 3,577 | 0 | - | - | Restricted Stock Units | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Apr 2018 | 18,333 | 417,407 (2%) | 0% | 0 | Common Stock | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 02 Apr 2018 | 250 | 399,074 (2%) | 0% | 0 | Common Stock | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.51 per share. | 02 Apr 2018 | 5,436 | 411,971 (2%) | 0% | 0.5 | 2,772 | Common Stock |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Apr 2018 | 18,333 | 91,668 | - | - | Restricted Stock Units | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Apr 2018 | 18,333 | 91,668 | - | - | Restricted Stock Units | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.51 per share. | 02 Apr 2018 | 5,766 | 411,535 (2%) | 0% | 0.5 | 2,941 | Common Stock |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Apr 2018 | 18,333 | 417,301 (2%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 02 Apr 2018 | 250 | 398,968 (2%) | 0% | 0 | Common Stock | |
| Jamie Bechtel Morrison | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2018 | 12,820 | 12,820 | - | - | Restricted Stock Units | |
| Jamie Bechtel Morrison | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2018 | 6,667 | 6,667 | - | - | Stock Option (right to buy) | |
| Andrew Altman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Jan 2018 | 50,000 | 0 | - | - | Restricted Stock Units | |
| Andrew Altman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 31 Jan 2018 | 50,000 | 78,112 (0%) | 0% | 0 | Common Stock | |
| Andrew Altman | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.70 per share. | 31 Jan 2018 | 17,375 | 60,737 (0%) | 0% | 0.7 | 12,163 | Common Stock |
| Julia Williams | None | Grant, award, or other acquisition of securities at price $ 0.72 per share. | 05 Jan 2018 | 37,162 | 137,510 (0%) | 0% | 0.7 | 26,757 | Common Stock |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2018 | 18,333 | 110,001 | - | - | Restricted Stock Units | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2018 | 18,333 | 405,310 (2%) | 0% | 0 | Common Stock | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.72 per share. | 02 Jan 2018 | 5,986 | 399,324 (2%) | 0% | 0.7 | 4,310 | Common Stock |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2018 | 18,333 | 110,001 | - | - | Restricted Stock Units | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2018 | 18,333 | 405,534 (2%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.72 per share. | 02 Jan 2018 | 6,316 | 399,218 (2%) | 0% | 0.7 | 4,548 | Common Stock |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 21 Dec 2017 | 5,000 | 392,977 (1%) | 0% | 0 | Common Stock | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.67 per share. | 21 Dec 2017 | 6,000 | 386,977 (1%) | 0% | 0.7 | 4,026 | Common Stock |
| Marc Dumont | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Dec 2017 | 3,086 | 3,086 (0%) | 0% | 0 | Common Stock | |
| Marc Dumont | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Dec 2017 | 3,086 | 0 | - | - | Restricted Stock Units | |
| Julia Williams | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Dec 2017 | 3,086 | 3,086 (0%) | 0% | 0 | Common Stock | |
| Julia Williams | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Dec 2017 | 3,086 | 0 | - | - | Restricted Stock Units | |
| Andrew Altman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Dec 2017 | 5,000 | 50,000 | - | - | Restricted Stock Units | |
| Andrew Altman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Dec 2017 | 5,000 | 28,112 (0%) | 0% | 0 | Common Stock | |
| Grover Turnbow Wickersham | Director | Grant, award, or other acquisition of securities at price $ 0.67 per share. | 18 Dec 2017 | 35,000 | 283,600 (0%) | 0% | 0.7 | 23,450 | Common Stock |
| Grover Turnbow Wickersham | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Dec 2017 | 3,086 | 286,686 (0%) | 0% | 0 | Common Stock | |
| Grover Turnbow Wickersham | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Dec 2017 | 3,086 | 0 | - | - | Restricted Stock Units | |
| Matthew K. Szot | Director | Grant, award, or other acquisition of securities at price $ 0.67 per share. | 18 Dec 2017 | 22,388 | 56,388 (0%) | 0% | 0.7 | 15,000 | Common Stock |
| Matthew K. Szot | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Dec 2017 | 3,086 | 0 | - | - | Restricted Stock Units | |
| Matthew K. Szot | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Dec 2017 | 3,086 | 3,086 (0%) | 0% | 0 | Common Stock | |
| Kim Patrice Wolin | EVP & Secretary | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.67 per share. | 18 Dec 2017 | 13,007 | 30,277 (0%) | 0% | 0.7 | 8,715 | Common Stock |
| Kim Patrice Wolin | EVP & Secretary | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2017 | 43,284 | 43,284 (0%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Sale of securities on an exchange or to another person at price $ 0.82 per share. | 04 Dec 2017 | 6,000 | 387,201 (1%) | 0% | 0.8 | 4,921 | Common Stock |
| Julia Williams | Director | Purchase of securities on an exchange or from another person at price $ 0.90 per share. | 24 Nov 2017 | 1,700 | 23,750 (0%) | 0% | 0.9 | 1,525 | Common Stock |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 0.89 per share. | 21 Nov 2017 | 6,000 | 397,977 (1%) | 0% | 0.9 | 5,363 | Common Stock |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 02 Nov 2017 | 40,000 | 399,201 (1%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Sale of securities on an exchange or to another person at price $ 2.72 per share. | 02 Nov 2017 | 6,000 | 393,201 (1%) | 0% | 2.7 | 16,339 | Common Stock |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 1.52 per share. | 20 Oct 2017 | 6,000 | 403,977 (1%) | 0% | 1.5 | 9,126 | Common Stock |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.85 per share. | 30 Sep 2017 | 5,014 | 409,977 (1%) | 0% | 1.9 | 9,276 | Common Stock |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Sep 2017 | 18,333 | 128,334 | - | - | Restricted Stock Units | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Sep 2017 | 18,333 | 414,991 (1%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Sep 2017 | 18,333 | 128,334 | - | - | Restricted Stock Units | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Sale of securities on an exchange or to another person at price $ 1.97 per share. | 30 Sep 2017 | 6,000 | 439,201 (1%) | 0% | 2.0 | 11,808 | Common Stock |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.85 per share. | 30 Sep 2017 | 5,344 | 445,201 (1%) | 0% | 1.8 | 9,886 | Common Stock |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Sep 2017 | 18,333 | 450,545 (1%) | 0% | 0 | Common Stock | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 1.79 per share. | 22 Sep 2017 | 6,000 | 396,658 (1%) | 0% | 1.8 | 10,740 | Common Stock |
| Andrew Altman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Sep 2017 | 5,000 | 55,000 | - | - | Restricted Stock Units | |
| Andrew Altman | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Sep 2017 | 5,000 | 25,000 (0%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Sale of securities on an exchange or to another person at price $ 2.31 per share. | 05 Sep 2017 | 6,000 | 430,212 (1%) | 0% | 2.3 | 13,834 | Common Stock |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 2.37 per share. | 21 Aug 2017 | 6,000 | 402,658 (1%) | 0% | 2.4 | 14,221 | Common Stock |
| Julia Williams | Director | Purchase of securities on an exchange or from another person at price $ 2.80 per share. | 16 Aug 2017 | 9,000 | 21,050 (0%) | 0% | 2.8 | 25,200 | Common Stock |
| Julia Williams | Director | Purchase of securities on an exchange or from another person at price $ 2.75 per share. | 16 Aug 2017 | 100 | 12,050 (0%) | 0% | 2.8 | 275 | Common Stock |
| Andrew Altman | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 2.82 per share. | 16 Aug 2017 | 1,000 | 3,600 (0%) | 0% | 2.8 | 2,820 | Common Stock |
| Andrew Altman | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 2.46 per share. | 16 Aug 2017 | 2,028 | 20,000 (0%) | 0% | 2.5 | 4,987 | Common Stock |
| Andrew Altman | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 2.81 per share. | 16 Aug 2017 | 14,372 | 17,972 (0%) | 0% | 2.8 | 40,332 | Common Stock |
| Andrew Altman | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 2.79 per share. | 16 Aug 2017 | 2,600 | 2,600 (0%) | 0% | 2.8 | 7,252 | Common Stock |
| Grover Turnbow Wickersham | Director | Purchase of securities on an exchange or from another person at price $ 3.04 per share. | 26 Jul 2017 | 10,000 | 248,600 (0%) | 0% | 3.0 | 30,442 | Common Stock |
| Julia Williams | Director | Purchase of securities on an exchange or from another person at price $ 3.21 per share. | 26 Jul 2017 | 10,000 | 11,950 (0%) | 0% | 3.2 | 32,099 | Common Stock |
| Grover Turnbow Wickersham | Director | Purchase of securities on an exchange or from another person at price $ 2.81 per share. | 25 Jul 2017 | 2,500 | 53,500 (0%) | 0% | 2.8 | 7,025 | Common Stock |
| Grover Turnbow Wickersham | Director | Purchase of securities on an exchange or from another person at price $ 2.86 per share. | 25 Jul 2017 | 12,500 | 238,600 (0%) | 0% | 2.9 | 35,750 | Common Stock |
| Thomas C. Chesterman | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 5.13 per share. | 17 Jul 2017 | 1,000 | 10,287 (0%) | 0% | 5.1 | 5,130 | Common Stock |
| Thomas C. Chesterman | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 5.15 per share. | 17 Jul 2017 | 393 | 9,876 (0%) | 0% | 5.2 | 2,024 | Common Stock |
| Thomas C. Chesterman | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 5.17 per share. | 17 Jul 2017 | 18 | 10,269 (0%) | 0% | 5.2 | 93 | Common Stock |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2017 | 73,333 | 146,667 | - | - | Restricted Stock Units | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.94 per share. | 30 Jun 2017 | 23,052 | 408,658 (1%) | 0% | 5.9 | 136,929 | Common Stock |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2017 | 73,333 | 431,710 (1%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.94 per share. | 30 Jun 2017 | 23,083 | 438,212 (1%) | 0% | 5.9 | 137,113 | Common Stock |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2017 | 73,333 | 461,295 (1%) | 0% | 0 | Common Stock | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2017 | 73,333 | 146,667 | - | - | Restricted Stock Units | |
| Andrew Altman | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2017 | 60,000 | 60,000 | - | - | Restricted Stock Units | |
| Thomas C. Chesterman | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 5.57 per share. | 08 Jun 2017 | 5,000 | 16,287 (0%) | 0% | 5.6 | 27,874 | Common Stock |
| Thomas C. Chesterman | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 5.85 per share. | 08 Jun 2017 | 4,000 | 12,287 (0%) | 0% | 5.9 | 23,400 | Common Stock |
| Thomas C. Chesterman | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 5.85 per share. | 08 Jun 2017 | 1,000 | 11,287 (0%) | 0% | 5.9 | 5,850 | Common Stock |
| Grover Turnbow Wickersham | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2017 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Grover Turnbow Wickersham | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2017 | 3,577 | 3,577 | - | - | Restricted Stock Units | |
| Marc Dumont | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2017 | 3,577 | 3,577 | - | - | Restricted Stock Units | |
| Marc Dumont | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2017 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Matthew K. Szot | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2017 | 3,577 | 3,577 | - | - | Restricted Stock Units | |
| Matthew K. Szot | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2017 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Bob Ramsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2017 | 3,577 | 3,577 | - | - | Restricted Stock Units | |
| Bob Ramsey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2017 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Julia Williams | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2017 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Julia Williams | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2017 | 3,577 | 3,577 | - | - | Restricted Stock Units | |
| Thomas C. Chesterman | CFO and Treasurer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.50 per share. | 20 Apr 2017 | 15,000 | 22,273 (0%) | 0% | 0.5 | 7,500 | Common Stock |
| Thomas C. Chesterman | CFO and Treasurer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Apr 2017 | 15,000 | 0 | - | - | Stock Option (Right to Buy) | |
| Thomas C. Chesterman | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 7.61 per share. | 20 Apr 2017 | 986 | 21,287 (0%) | 0% | 7.6 | 7,503 | Common Stock |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 11 Apr 2017 | 1,000 | 373,377 (1%) | 0% | 0 | Common Stock | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 11 Apr 2017 | 15,000 | 358,377 (1%) | 0% | 0 | Common Stock | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 11 Apr 2017 | 4,900 | 374,377 (1%) | 0% | 0 | Common Stock | |
| Marc Dumont | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Feb 2017 | 89 | 89 (0%) | 0% | 0 | Common Stock | |
| Julia Williams | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 22 Feb 2017 | 60 | 97,262 (0%) | 0% | 0 | Common Stock | |
| Julia Williams | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 22 Feb 2017 | 537 | 97,202 (0%) | 0% | 0 | Common Stock | |
| Julia Williams | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 02 Feb 2017 | 4,000 | 4,000 (0%) | 0% | 0 | Common Stock | |
| Julia Williams | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 02 Feb 2017 | 4,100 | 96,665 (0%) | 0% | 0 | Common Stock | |
| Julia Williams | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 02 Feb 2017 | 4,000 | 100,765 (0%) | 0% | 0 | Common Stock | |
| Grover Turnbow Wickersham | Director | Purchase of securities on an exchange or from another person at price $ 7.45 per share. | 27 Jan 2017 | 1,600 | 226,100 (0%) | 0% | 7.4 | 11,913 | Common Stock |
| Bob Ramsey | Director | Purchase of securities on an exchange or from another person at price $ 7.46 per share. | 27 Jan 2017 | 7,000 | 27,000 (0%) | 0% | 7.5 | 52,189 | Common Stock |
| Julia Williams | Director | Purchase of securities on an exchange or from another person at price $ 7.94 per share. | 27 Jan 2017 | 1,950 | 1,950 (0%) | 0% | 7.9 | 15,483 | Common Stock |
| Grover Turnbow Wickersham | Director | Purchase of securities on an exchange or from another person at price $ 7.42 per share. | 24 Jan 2017 | 1,000 | 51,000 (0%) | 0% | 7.4 | 7,415 | Common Stock |
| Thomas C. Chesterman | CFO and Treasurer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2016 | 10,494 | 0 | - | - | Restricted Stock Units | |
| Thomas C. Chesterman | CFO and Treasurer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2016 | 10,494 | 10,494 | - | - | Common Stock | |
| Thomas C. Chesterman | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 27 Dec 2016 | 3,221 | 7,273 | - | - | Common Stock | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2016 | 5,556 | 0 | - | - | Restricted Stock Units | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2016 | 5,556 | 381,032 | - | - | Common Stock | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 27 Dec 2016 | 1,755 | 379,277 | - | - | Common Stock | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2016 | 3,241 | 0 | - | - | Restricted Stock Units | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2016 | 3,241 | 388,957 | - | - | Common Stock | |
| Cheryl A. Dyer | Director, Pres. & Chief Research Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 27 Dec 2016 | 995 | 387,962 | - | - | Common Stock | |
| Thomas C. Chesterman | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2016 | 10,494 | 10,494 | - | - | Restricted Stock Units | |
| Grover Turnbow Wickersham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2016 | 3,086 | 3,086 | - | - | Restricted Stock Units | |
| Grover Turnbow Wickersham | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2016 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Marc Dumont | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2016 | 3,086 | 3,086 | - | - | Restricted Stock Units | |
| Marc Dumont | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2016 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Matthew K. Szot | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2016 | 3,086 | 3,086 | - | - | Restricted Stock Units | |
| Matthew K. Szot | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2016 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Loretta P. Mayer | Director, CEO & Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2016 | 5,556 | 5,556 | - | - | Restricted Stock Units | |
| Cheryl A. Dyer | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2016 | 3,241 | 3,241 | - | - | Restricted Stock Units | |
| Bob Ramsey | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2016 | 3,086 | 3,086 | - | - | Restricted Stock Units | |
| Bob Ramsey | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2016 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Julia Williams | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2016 | 3,086 | 3,086 | - | - | Restricted Stock Units | |
| Julia Williams | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2016 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Grover Turnbow Wickersham | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 13 Dec 2016 | 10,000 | 224,500 | - | - | Common Stock | |
| Grover Turnbow Wickersham | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 13 Dec 2016 | 10,000 | 33,000 | - | - | Common Stock | |
| Grover Turnbow Wickersham | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 13 Dec 2016 | 5,000 | 50,000 | - | - | Common Stock | |
| Grover Turnbow Wickersham | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 13 Dec 2016 | 32,500 | 392,500 | - | - | Common Stock | |
| Grover Turnbow Wickersham | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 13 Dec 2016 | 5,000 | 7,000 | - | - | Common Stock | |
| Julia Williams | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 13 Dec 2016 | 1,000 | 1,000 | - | - | Common Stock |